El Reno is a city in Canadian County, Oklahoma in the central part of the state. El Reno, part of the Oklahoma City Metropolitan Statistical Area, is 25 miles west of downtown Oklahoma City. The population was 16,212 at the 2000 census. It is the county seat of Canadian County^GR6.

Strategically located at the interchange of I-40 and U.S. Route 81, El Reno is within easy access to both I-44 and I-35. Redlands Community College provides convenient, state-of-the-art training.

Historical Fort Reno was built in 1874. Today, the grounds of the old fort are home to a research laboratory for the U.S. Department of Agriculture. The laboratory studies environmentally sustainable forage and livestock production, contributing to preservation of the great plains of North America.

El Reno is an active Main Street community. The Oklahoma Main Street Program is a downtown revitalization program.

El Reno was formerly a Certified City and has successfully transitioned to a Century Community.