McDermitt is an unincorporated town straddling the Nevada-Oregon border, in Humboldt County, Nevada and Malheur County, Oregon. The town, originally called Dugout, was named after Charles McDermit (sic), a commander of the Military District of Nevada in the 1860s. It was originally established to protect a stagecoach route from Virginia City, Nevada to Boise, Idaho.

As of the 2000 census, the CDP population was 269, a precipitous decline from the 373 people enumerated in the census a decade earlier.

The town is on U.S. Highway 95. Its economy has historically been based on ranching and farming, and home to a mercury mine until 1990. Mining may start up in the area again, courtesy of Canadian firm Gold Canyon Resources . Samples from a former mercury mine in the area suggest that it could become home to the world's only gallium mine, which is normally produced as a by-product of aluminum and zinc mining.

The state line goes through the White Horse Inn, a now-abandoned saloon, hotel, and reportedly, brothel . When it was open, you could order your food in Oregon, thus avoiding Nevada sales tax .