Biloxi ([bəˈlʌksi]) is a city in Harrison County, Mississippi, in the United States. The 2000 census recorded the population as 50,644. The city is co–county seat with Gulfport. On August 29, 2005, Biloxi was severely damaged by Hurricane Katrina, which struck with a 30-foot (9-meter) storm surge. In the center of what fisheries biologists term "The Fertile Fisheries Crescent", Biloxi offered some of the finest sportsfishing along the entire northern coast of the Gulf of Mexico. Spotted seatrout, red drum, Spanish and king mackerel, flounder, snapper, grouper, sharks, and more are all available to anglers during the fishing season. It is not known how Hurricane Katrina affected this biosystem.

Keesler Air Force Base lies within the city and is home to the 81st Training Wing of the U.S. Air Force.

With the introduction of gambling in Mississippi in the 1990s, Biloxi became an important center for casinos; the hotels and complexes brought millions of dollars in tourism revenue to the city. The more famous casino complexes were the Beau Rivage casino resort, Casino Magic, Grand Casino, Boomtown Casino, and Imperial Palace. Like Tunica County in the northern part of the state, Biloxi and the surrounding Gulf Coast region was considered a leading gambling center in the Southern United States until many casinos were damaged or destroyed by Hurricane Katrina on August 29, 2005.

The city is home to the Mississippi Sea Wolves, an East Coast Hockey League minor league hockey team. The city hosted the National Ocean Sciences Bowl Competition in May 2005. Biloxi and the Mississippi Gulf Coast is now home to its first all-female flat track derby league, the Mississippi Rollergirls. http://www.mississippirollergirls.com