Portland is the largest city in the U.S. state of Maine, with a population of 63,882 as of 2004 (down from 64,249 in 2000). It is the county seat of Cumberland County. Nearby cities include Boston, Massachusetts, Portsmouth, New Hampshire and Manchester, New Hampshire. It is popular with tourists visiting the state because of its lively downtown and historic Old Port district along Portland Harbor, which is at the mouth of the Fore River. The Portland Head Light in nearby Cape Elizabeth is a popular tourist attraction often used as a symbol of the harbor and surrounding towns.

Portland is Maine's cultural and economic capital, and it is a major draw for residents statewide. The city is politically liberal, leading many Mainers to consider it culturally different from other sections of the state.

The city seal is a phoenix rising out of ashes, which goes with its motto, "Resurgam," which means "I will rise again", in reference to fires that burned much of the city.

The city of Portland, Oregon was named for Portland, Maine. The Portland Public Schools are the largest school district in Maine.