Nome is a city located on the southern Seward Peninsula coast of Norton Sound in the Nome Census Area of the U.S. state of Alaska. As of the 2000 census, the city population was 3,505. Briefly at its founding in 1898, it was called Anvil City. Nome was incorporated in 1901, and its now within the Sitnasuak Native Corporation lands. The city of Nome also claims to be home to the world's largest gold pan, although this claim has been disputed by the city of Quesnel, B.C., Canada.

In the winter of 1925, a diphtheria epidemic among Eskimos in Nome was halted when, during fierce blizzard conditions, a sled team arrived with serum. The sled driver of the final leg of the relay was Gunnar Kaasen and the lead sled dog was Balto. A statue of Balto by F.G. Roth stands near the zoo in Central Park, New York, as does one in downtown Anchorage, Alaska. The annual Iditarod sled-dog race commemorates this historic event.